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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK1
All Species:
15.76
Human Site:
S357
Identified Species:
34.67
UniProt:
Q8TDC3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDC3
NP_115806.1
794
86753
S357
R
L
H
R
E
L
R
S
E
E
E
N
Q
E
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541413
801
87720
S364
R
L
H
R
E
L
R
S
E
E
E
N
Q
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJI5
778
85136
S341
R
L
H
R
E
L
R
S
E
E
E
N
Q
E
K
Rat
Rattus norvegicus
O08679
722
80853
R292
L
I
L
N
P
S
K
R
G
T
L
E
Q
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514667
306
34673
Chicken
Gallus gallus
Q9IA88
798
88848
N327
R
T
V
E
S
L
Q
N
S
S
Y
N
H
F
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S376
S
A
T
Y
S
L
L
S
D
K
L
K
R
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
S324
K
L
I
Q
E
L
L
S
S
S
H
N
T
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S486
L
L
L
G
E
R
K
S
D
M
D
A
S
E
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
V108
H
I
I
R
L
Y
E
V
I
E
T
P
T
D
I
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
Q443
L
I
T
A
K
L
L
Q
K
P
M
S
E
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98.1
N.A.
94.8
29.2
N.A.
32.1
28.3
N.A.
25.1
N.A.
48.5
N.A.
25.7
N.A.
Protein Similarity:
100
N.A.
N.A.
98.2
N.A.
95.4
44.5
N.A.
33.3
43.9
N.A.
38.5
N.A.
62.5
N.A.
37.9
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
6.6
N.A.
0
20
N.A.
20
N.A.
46.6
N.A.
26.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
20
N.A.
0
33.3
N.A.
40
N.A.
60
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
34.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
19
0
10
0
0
10
0
% D
% Glu:
0
0
0
10
46
0
10
0
28
37
28
10
10
55
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
10
0
28
0
0
0
0
0
0
0
10
0
10
10
0
% H
% Ile:
0
28
19
0
0
0
0
0
10
0
0
0
0
10
19
% I
% Lys:
10
0
0
0
10
0
19
0
10
10
0
10
0
0
55
% K
% Leu:
28
46
19
0
10
64
28
0
0
0
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
0
46
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
10
0
0
0
0
37
0
0
% Q
% Arg:
37
0
0
37
0
10
28
10
0
0
0
0
10
0
0
% R
% Ser:
10
0
0
0
19
10
0
55
19
19
0
10
10
0
0
% S
% Thr:
0
10
19
0
0
0
0
0
0
10
10
0
19
0
0
% T
% Val:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _